Metaxalone + Oxycodone Hydrochloride Interaction
Unknowninteraction on record
Description
Due to the risk of respiratory depression with concomitant use of skeletal muscle relaxants and opioids, consider recommending or prescribing an opioid overdose reversal agent [ see Dosage and Administration ( 2.2 ), Warnings and Precautions ( 5.2 , 5.3 ) ] Examples: Cyclobenzaprine, metaxolone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone.
Source: FDA drug label - oxycodone hydrochloride