Macitentan + Ritonavir Interaction
Majorinteraction on record
Description
• Strong CYP3A4 inhibitors (ketoconazole, ritonavir) increase exposure to macitentan: avoid co-administration with macitentan ( 7.2 , 12.3 ). Many HIV drugs like ritonavir are strong inhibitors of CYP3A4.
Source: FDA drug label - macitentan