Losartan Potassium And Hydrochlorothiazide + Ketoconazole Interaction

Unknowninteraction on record

Description

Conversion of losartan to its active metabolite after intravenous administration is not affected by ketoconazole, an inhibitor of P450 3A4. Ketoconazole did not affect the conversion of losartan to the active metabolite after intravenous administration of losartan, and erythromycin had no clinically significant effect after oral administration.

Source: FDA drug label - losartan potassium and hydrochlorothiazide