Lansoprazole%2C Amoxicillin%2C Clarithromycin + Triazolam Interaction

Moderateinteraction on record

Description

Alprazolam Triazolam Triazolam, Alprazolam : Caution and appropriate dose adjustments should be considered when triazolam or alprazolam is coadministered with clarithromycin. There have been postmarketing reports of drug interactions and central nervous system (CNS) effects (e.g., somnolence and confusion) with the concomitant use of clarithromycin and triazolam. In postmarketing experience, erythromycin has been reported to decrease the clearance of triazolam and midazolam, and thus, may increase the pharmacologic effect of these benzodiazepines.

Source: FDA drug label - lansoprazole, amoxicillin, clarithromycin