Ketoconazole + Methylprednisolone Acetate%2C Lidocaine Hydrochloride%2C Bupivacaine Hydrochloride%2C Povidine Iodine%2C Sodium Chloride%2C Isopropyl Alcohol Interaction
Moderateinteraction on record
Description
Hepatic Enzyme Inhibitors (e.g., ketoconazole, macrolide antibiotics such as erythromycin and troleandomycin): Drugs which inhibit cytochrome P450 3A4 have the potential to result in increased plasma concentrations of corticosteroids. Ketoconazole : Ketoconazole has been reported to significantly decrease the metabolism of certain corticosteroids by up to 60%, leading to an increased risk of corticosteroid side effects.
Source: FDA drug label - methylprednisolone acetate, lidocaine hydrochloride, bupivacaine hydrochloride, povidine iodine, isopropyl alcohol