Ketoconazole + Depo Medrol%2C Lidocaine%2C Isopropyl Alcohol Interaction

Moderateinteraction on record

Description

Hepatic Enzyme Inhibitors (e.g., ketoconazole, macrolide antibiotics such as erythromycin and troleandomycin): Drugs which inhibit cytochrome P450 3A4 have the potential to result in increased plasma concentrations of corticosteroids. Ketoconazole : Ketoconazole has been reported to significantly decrease the metabolism of certain corticosteroids by up to 60%, leading to an increased risk of corticosteroid side effects.

Source: FDA drug label - depo-medrol, lidocaine, isopropyl alcohol