Itraconazole + Busulfan Interaction
Unknowninteraction on record
Description
7 DRUG INTERACTIONS Drugs that Decrease Busulfan Clearance: Metronidazole, itraconazole, iron chelating agents, acetaminophen. ( 7.2 ) 7.1 Drugs that Decrease Busulfan Clearance Itraconazole decreases busulfan clearance by up to 25%. Metronidazole decreases the clearance of busulfan to a greater extent than does itraconazole; metronidazole coadministration has been associated with increased busulfan toxicity.
Source: FDA drug label - busulfan