Glyburide And Metformin Hydrochloride + Nifedipine Interaction
Minorinteraction on record
Description
Nifedipine A single-dose, metformin-nifedipine drug interaction study in normal healthy volunteers demonstrated that coadministration of nifedipine increased plasma metformin C max and AUC by 20% and 9%, respectively, and increased the amount excreted in the urine. Nifedipine appears to enhance the absorption of metformin. Metformin had minimal effects on nifedipine.
Source: FDA drug label - glyburide and metformin hydrochloride