Fluconazole + Rifabutin Interaction
Moderateinteraction on record
Description
Therefore, carefully monitor for rifabutin associated adverse events in those patients also receiving CYP3A inhibitors, which include fluconazole and clarithromycin. ANTIFUNGALS Fluconazole 200 mg once a day for 2 weeks 300 mg once a day for 2 weeks HIV infected patients (12) ↑ AUC by 82%, ↑ C max by 88% Monitor for rifabutin associated adverse events.
Source: FDA drug label - rifabutin