Elfinavir + Omeprazole Interaction

Unknowninteraction on record

Description

7 DRUG INTERACTIONS • Atazanavir and nelfinavir: Omeprazole reduces plasma levels of atazanavir and nelfinavir. voriconazole) may raise omeprazole levels ( 7.3 ) • Tacrolimus: Omeprazole may increase serum levels of tacrolimus ( 7.4 ) • Methotrexate: Omeprazole may increase serum levels of methotrexate ( 7.7 ) 7.1 Interference with Antiretroviral Therapy Concomitant use of atazanavir and nelfinavir with proton pump inhibitors is not recommended. Reduced concentrations of atazanavir and nelfinavir For some antiretroviral drugs, such as atazanavir and nelfinavir, decreased serum levels have been reported when given together with omeprazole.

Source: FDA drug label - omeprazole