Efavirenz%2C Emtricitabine And Tenofovir Disoproxil Fumarate + Darunavir Interaction
Moderateinteraction on record
Description
( 4 , 5.4 , 7 ) • HIV-1 protease inhibitors: Coadministration of efavirenz, emtricitabine and tenofovir disoproxil fumarate with either lopinavir/ritonavir or darunavir and ritonavir increases tenofovir concentrations. Protease inhibitor: darunavir/ritonavir lopinavir/ritonavir ↑ tenofovir ↓ lopinavir ↑ tenofovir Monitor patients receiving efavirenz, emtricitabine and tenofovir disoproxil fumarate concomitantly with ritonavir-boosted darunavir for TDF-associated adverse reactions.
Source: FDA drug label - efavirenz, emtricitabine and tenofovir disoproxil fumarate