Darunavir + Rifabutin Interaction
Unknowninteraction on record
Description
Darunavir/ Ritonavir 600/100 mg twice a day for 12 days 150 mg every other day for 12 days Healthy HIV negative adults No significant change in rifabutin pharmacokinetics. 881% ↑in AUC, 377% ↑ C max of 25-O-desacetyl-rifabutin 57% ↑in AUC, 42% ↑ C max of darunavir.
Source: FDA drug label - rifabutin