Clarithromycin + Disopyramide Phosphate Interaction
Majorinteraction on record
Description
Cases of life-threatening interactions have been reported for disopyramide when given with clarithromycin and erythromycin indicating that coadministration of disopyramide with inhibitors of cytochrome P450 3A4 could result in potentially fatal interaction.
Source: FDA drug label - disopyramide phosphate