Carbenicillin + Gentamicin Sulfate Interaction
Majorinteraction on record
Description
Although the in vitro mixing of gentamicin and carbenicillin results in a rapid and significant inactivation of gentamicin, this interaction has not been demonstrated in patients with normal renal function who received both drugs by different routes of administration. A reduction in gentamicin serum half-life has been reported in patients with severe renal impairment receiving carbenicillin concomitantly with gentamicin.
Source: FDA drug label - gentamicin sulfate