Atazanavir And Cobicistat + Ivosidenib Interaction
Contraindicatedinteraction on record
Description
ivosidenib ↓ atazanavir ↓ cobicistat ↑ ivosidenib Coadministration with ivosidenib is contraindicated due to the potential for loss of virologic response of EVOTAZ, development of resistance, and risk of serious adverse events such as QT interval prolongation. Mechanism: The mechanism of interaction is CYP3A4 induction by ivosidenib.
Source: FDA drug label - atazanavir and cobicistat