Aliskiren Hemifumarate + Aldosterone Interaction

Moderateinteraction on record

Description

Dual Blockade of the Renin-Angiotensin-Aldosterone System (RAAS): The concomitant use of aliskiren with other agents acting on the RAAS such as ACEIs or ARBs is associated with an increased risk of hypotension, hyperkalemia, and changes in renal function (including acute renal failure) compared to monotherapy.

Source: FDA drug label - aliskiren hemifumarate