Aldosterone + Promethazine%2C Phenylephrine%2C Codeine Interaction
Description
( 7.10 ) Ergot alkaloids, atropine sulfate, steroids, angiotensin, aldosterone, norepinephrine transporter inhibitors, and tricyclic antidepressants : Concomitant use may enhance the pressor response and increase the risk of hypertension. 7.11 Interactions that Augment the Pressor Effect of Phenylephrine The concomitant use of Promethazine and Phenylephrine HCl and Codeine Phosphate Oral Solution with ergot alkaloids (e.g., methylergonovine maleate); atropine sulfate; steroids (e.g., hydrocortisone); angiotensin; aldosterone; norepinephrine transporter inhibitors (e.g., atomoxetine); and tricyclic antidepressants may enhance the pressor response and increase the risk of hypertension.
Source: FDA drug label - promethazine, phenylephrine, codeine