Acetazolamide + Sulfamethoxazole And Trimethoprim Interaction

Unknowninteraction on record

Description

Sulfonamides can also displace methotrexate from plasma protein binding sites and can compete with the renal transport of methotrexate, thus increasing free methotrexate concentrations. Like other sulfonamide-containing drugs, sulfamethoxazole and trimethoprim potentiates the effect of oral hypoglycemics.

Source: FDA drug label - sulfamethoxazole and trimethoprim