Methylprednisolone Acetate, Lidocaine Hydrochloride, Povidine Iodine, Isopropyl Alcohol Interactions

Hepatic Enzyme Inhibitors (e.g., ketoconazole, macrolide antibiotics such as erythromycin and troleandomycin): Drugs which inhibit cytochrome P450 3A4 have the potential to result in increased plasma concentrations of corticosteroids. Ketoconazole : Ketoconazole has been reported to significantly decrease the metabolism of certain corticosteroids by up to 60%, leading to an increased risk of corticosteroid side effects.

Source: FDA drug label - methylprednisolone acetate, lidocaine hydrochloride, povidine iodine, isopropyl alcohol

Drug Interactions Aminoglutethimide : Aminoglutethimide may lead to a loss of corticosteroid-induced adrenal suppression.

Source: FDA drug label - methylprednisolone acetate, lidocaine hydrochloride, povidine iodine, isopropyl alcohol

Hepatic Enzyme Inhibitors (e.g., ketoconazole, macrolide antibiotics such as erythromycin and troleandomycin): Drugs which inhibit cytochrome P450 3A4 have the potential to result in increased plasma concentrations of corticosteroids.

Source: FDA drug label - methylprednisolone acetate, lidocaine hydrochloride, povidine iodine, isopropyl alcohol

Hepatic Enzyme Inhibitors (e.g., ketoconazole, macrolide antibiotics such as erythromycin and troleandomycin): Drugs which inhibit cytochrome P450 3A4 have the potential to result in increased plasma concentrations of corticosteroids.

Source: FDA drug label - methylprednisolone acetate, lidocaine hydrochloride, povidine iodine, isopropyl alcohol