Zolpidem Tartrate Sublingual Interactions

Brand names: Zolpidem Tartrate Sublingual

FDA Black Box Warning

WARNING: COMPLEX SLEEP BEHAVIORS Complex sleep behaviors including sleep-walking, sleep-driving, and engaging in other activities while not fully awake may occur following use of zolpidem tartrate. Some of these events may result in serious injuries, including death. Discontinue zolpidem tartrate immediately if a patient experiences a complex sleep behavior [see Contraindications (4) and Warnings and Precautions (5.1)]. WARNING: COMPLEX SLEEP BEHAVIORS See full prescribing information for complete box warning. Complex sleep behaviors including sleep-walking, sleep-driving, and engaging in other activities while not fully awake may occur following use of zolpidem tartrate. Some of these events may result in serious injuries, including death. Discontinue zolpidem tartrate immediately if a patient experiences a complex sleep behavior (4, 5.1).

1 interaction on record

Zolpidem Tartrate Sublingual + KetoconazoleUnknown

7 DRUG INTERACTIONS CNS depressants, including alcohol: Possible adverse additive CNS depressant effects (5.1, 7.1) Imipramine: Decreased alertness observed (7.1) Chlorpromazine: Impaired alertness and psychomotor performance observed (7.1) Rifampin: Combination use may decrease effects (7.2) Ketoconazole: Combination use may increase effects (7.2) 7.1 CNS-active Drugs Co-administration of zolpidem with other CNS depressants increases the risk of CNS depression [see Warnings and Precautions (5.1, 5.2)]. Ketoconazole Ketoconazole, a potent CYP3A4 inhibitor, increased the pharmacodynamic effects of zolpidem. Consideration should be given to using a lower dose of zolpidem when ketoconazole and zolpidem are given together.

Source: FDA drug label - zolpidem tartrate sublingual