Pravastatin Clinical Impact: Concomitant use of NEXLETOL with pravastatin causes an increase in pravastatin concentration and may increase the risk of pravastatin-related myopathy [see Clinical Pharmacology (12.3) ] . Intervention: Avoid concomitant use of NEXLETOL with pravastatin greater than 40 mg. ( 7 ) Pravastatin: Avoid concomitant use of NEXLETOL with pravastatin greater than 40 mg.
Source: FDA drug label - bempedoic acid