Deferiprone Interactions

FDA Black Box Warning

WARNING: AGRANULOCYTOSIS AND NEUTROPENIA • Deferiprone tablets can cause agranulocytosis that can lead to serious infections and death. Neutropenia may precede the development of agranulocytosis. [see Warnings and Precautions ( 5.1 )] • Measure the absolute neutrophil count (ANC) before starting deferiprone tablets therapy and monitor regularly while on therapy. • Interrupt deferiprone tablets therapy if neutropenia develops. [see Warnings and Precautions ( 5.1 )] • Interrupt deferiprone tablets if infection develops, and monitor the ANC more frequently. [see Warnings and Precautions ( 5.1 )] • Advise patients taking deferiprone tablets to report immediately any symptoms indicative of infection. [see Warnings and Precautions ( 5.1 )] WARNING: AGRANULOCYTOSIS AND NEUTROPENIA See full prescribing information for complete boxed warning. • Deferiprone tablets can cause agranulocytosis that can lead to serious infections and death. Neutropenia may precede the development of agranulocytosis. ( 5.1 ) • Measure the absolute neutrophil count (ANC) before starting deferiprone tablets and monitor regularly while on therapy. ( 5.1 ) • Interrupt deferiprone tablets therapy if neutropenia develops. ( 5.1 ) • Interrupt deferiprone tablets if infection develops and monitor the ANC more frequently. ( 5.1 ) • Advise patients taking deferiprone tablets to report immediately any symptoms indicative of infection. ( 5.1 )